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This site is intended for U.S. Healthcare Professionals.
To report an adverse event or product quality complaint, call 1-877-TAKEDA-7 (1-877-825-3327)
Not an actual patient.
Approximately 1.6 million Americans have IBD,1,2 which is comprised of 2 major types: ulcerative colitis (UC), characterized by continuous, mucosal inflammation limited to the innermost lining of the colon and rectum, and Crohn’s disease (CD), defined by patchy, transmural inflammation which can affect any part of the gastrointestinal (GI) tract, from the mouth to the perianal area.1,3,4
Population-based studies in the U.S. suggest that the incidence of IBD is most common in patients aged 15 to 35 years.1 IBD can also present in childhood, including up to 20% of children who are diagnosed before the age of 10 years.5 It is more common in Whites (vs other racial groups) and in adults, UC is more common in males.1,6
Symptoms of IBD depend on the disease location, and can range from mild to moderate to severe.2,4 Diarrhea and rectal bleeding are characteristic with UC. Patients can experience weight loss and fever (although it can be less common than with CD), and abdominal pain varies depending on the patient. For CD, weight loss, fever, and abdominal pain are more predominant, although these patients can also experience diarrhea and rectal bleeding.4
Irritable bowel syndrome (IBS), the most common GI condition diagnosed by gastroenterologists, may be mistaken for IBD since IBS symptoms may mimic those seen in a patient with mild IBD, but history and additional diagnostic tests can help rule it out of the differential diagnosis.7 Endoscopy combined with biopsies of the affected area(s) of the GI tract will also establish the diagnosis and differentiate between UC and CD.4,8
The etiology of IBD most likely involves a complex interaction between genetic and environmental factors, microbiome, and the immune system.3,4 T cells, which are activated by antigen-presenting cells in the peripheral lymphoid tissue, migrate to the site of inflammation and play a role in recruitment and activation of additional inflammatory cells in the GI tract.9,10
IBD is a chronic disease, with significant impact on a patient’s general health.3 While the Crohn’s Disease Activity Index (for CD) and Mayo Score (for UC) are the most frequently used instruments for scoring and monitoring disease activity in clinical trials, researchers are working to improve the measures of disease activity and severity through assessment of impact of disease on the patient, disease burden, and disease course, including structural damage with a goal of improving disease management for patients.11
Annual global congress dedicated to clinical nutrition and metabolism, including basic and clinical research, education, and organization of consensus statements about clinical care.
Global congress for researchers from around the world to present their findings on gastroenterology and digestive health.
Annual event dedicated to excellence in clinical pharmacy practice, research, and education.
Annual event with more than 2,500 members and non-members of the AMCP to engage on the latest innovations and most intentional networking in managed care pharmacy.
Global meeting featuring thought leaders from around the world focused on advancing patient care in allergy and immunology.
Premier event for clinicians and the general public about digestive disorders and the latest trends in GI technology and therapeutics.
Annual forum for participants to learn about the latest advances in pediatric gastroenterology, hepatology, and nutrition, and to discuss current topics in clinical applications.
An all-encompassing event providing real-world clinical education, case studies and new evidence-based approaches in IBD management.
Global meeting for physicians, researchers, and industry in the fields of gastroenterology, hepatology, endoscopy, and gastrointestinal surgery.
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Large assembly of pharmacy and healthcare professionals dedicated to the issues of managed care pharmacy, offering immersive education sessions and keynote presentations.
International meeting concerning the field of Eosinophilic Gastrointestinal Disorders, including EoE and other eosinophilic diseases.
Annual global conference for interdisciplinary, clinical nutrition leaders, providing the latest in clinical nutrition research, education, and products.
Premier global educational event for allergists and immunologists, with thousands of attendees each year, discussing allergies, asthma, and immune deficiency disorders.
Annual global congress structured around basic science, traditional medicine and clinical sessions given by some of the world's top GI specialists.
Annual conference for a multidisciplinary community of practitioners and researchers focusing on inflammatory bowel disease (IBD) by pairing best practices in clinical care with innovative research.
An all-encompassing event providing real-world clinical education, case studies and new evidence-based approaches in IBD management.
Premier event for clinicians and the general public about digestive disorders and the latest trends in GI technology and therapeutics.
Annual event with more than 2,500 members and non-members of the AMCP to engage on the latest innovations and most intentional networking in managed care pharmacy.
Global congress for researchers from around the world to present their findings on gastroenterology and digestive health.
Annual forum for participants to learn about the latest advances in pediatric gastroenterology, hepatology, and nutrition, and to discuss current topics in clinical applications.
Annual global congress dedicated to clinical nutrition and metabolism, including basic and clinical research, education, and organization of consensus statements about clinical care.
Annual meeting uncovering cutting-edge research ranging from basic neurogastroenterology, translational and clinical aspects of gastrointestinal motility, and functional disorders.
Medication Resources
(vedolizumab)
Videos
Watch videos focused on inflammatory bowel disease (IBD).
Learn about how inflammation in the intestinal tract can lead to inflammatory bowel disease (IBD).